聽聽聽
聽聽聽本法系利用抗生素在琼脂培养基内的扩散作用，采用量反应平行线原理的设计，比
较标准品与供试品两者对接种的试验菌产生抑菌圈的大小，以测定供试品效价的一种方
法。
聽聽聽聽标准品的品种、分子式及理论计算值见下表。
聽聽聽聽聽聽聽聽聽聽聽聽聽聽表2聽抗生素标准品品种与理论值
┏━━━━━━━┯━━━━━━━━━━━━━━━━┯━━━━━━━━┓
┃聽聽标准品品种聽聽│聽聽聽聽标准品分子式或品名聽聽聽聽聽聽聽聽聽聽│理论计算值聽u/mg聽┃
┠───────┼────────────────┼────────┨
┃链霉素　　　　│(C21H39N7O12)2·3H2SO4聽聽聽聽聽聽聽聽聽聽│聽聽798聽聽聽聽聽聽聽聽聽聽聽┃
┃卡那霉素聽聽聽聽聽聽│C18H36N4O11·H2SO4聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽831.6聽聽聽聽聽聽聽聽聽┃
┃阿米卡星聽聽聽聽聽聽│C22H43N5O13聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽1000聽聽聽聽聽聽聽聽聽聽聽┃
┃核糖霉素聽聽聽聽聽聽│C17H34N4O10·nH2SO4(n<2)聽聽聽聽聽聽聽聽│聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽┃
┃新霉素聽聽聽聽聽聽聽聽│硫酸新霉素聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽┃
┃庆大霉素聽聽聽聽聽聽│硫酸庆大霉素聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽┃
┃磺苄西林聽聽聽聽聽聽│C16H16N2Na2O7S2聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽┃
┃头胞噻肟钠聽聽聽聽│C16H16N5NaO7S2聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽951.85聽聽聽聽聽聽聽聽┃
┃四环素聽聽聽聽聽聽聽聽│C22H24N2O8·HCl聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽1000聽聽聽聽聽聽聽聽聽聽聽┃
┃土霉素聽聽聽聽聽聽聽聽│C22H24N2O9·2H2O聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽927聽聽聽聽聽聽聽聽聽聽聽┃
┃美他环素聽聽聽聽聽聽│C22H22N2O8·HCl　聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽923.86聽聽聽聽聽聽聽聽┃
┃金霉素聽聽聽聽聽聽聽聽│C22H23ClN2O8·HCl聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽1000聽聽聽聽聽聽聽聽聽聽聽┃
┃多西环素聽聽聽聽聽聽│C22H24N2O8HCl·1/2C2H5OH·1/2H2O│聽聽866.45聽聽聽聽聽聽聽聽┃
┃红霉素聽聽聽聽聽聽聽聽│C37H67NO13聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽1000聽聽聽聽聽聽聽聽聽聽聽┃
┃氯霉素聽聽聽聽聽聽聽聽│C11H12Cl2N2O5聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽1000聽聽聽聽聽聽聽聽聽聽聽┃
┃杆菌肽聽聽聽聽聽聽聽聽│杆肽菌聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽┃
┃粘菌素聽聽聽聽聽聽聽聽│硫酸粘菌素聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽┃
┃去甲万古霉素聽聽│C65H73Cl2N9O24·HCl聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽975.23聽聽聽聽聽聽聽聽┃
┃卷曲霉素聽聽聽聽聽聽│硫酸卷曲霉素聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽┃
┃两性霉素B聽聽聽聽聽│C47H73NO17聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽│聽1000聽聽聽聽聽聽聽聽聽聽聽┃
┗━━━━━━━┷━━━━━━━━━━━━━━━━┷━━━━━━━━┛


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